International Scholarships

Wednesday, 10 October 2007

Bisulfite Conversion and Sequencing of Methylated DNA

methylSEQr™ System: Bisulfite Conversion and Sequencing of Methylated DNA
Applied Biosystems

DNA methylation patterns—are often considered as a second code, an additional layer of information superimposed on the DNA code that determines many phenotypic attributes. The DNA code is stable, but DNA methylation patterns change in response to spatial, temporal and environmental cues. After PCR amplification, the sequence of the bisulfite converted DNA will have C residues only if the C was methylated and will occur adjacent to G's (CpG). A...

http://www.biotechniques.com/default.asp?page=protocol&subsection=article_display&id=112346

No comments:

Current Posts at Oxford Laboratory Technology

usa-bg

usa-bg
usa-bg